Review of hepatocellular carcinoma: Epidemiology, etiology, and carcinogenesis

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منابع مشابه

Review of hepatocellular carcinoma: Epidemiology, etiology, and carcinogenesis

Since the 1970s, the epidemic of hepatocellular carcinoma (HCC) has spread beyond the Eastern Asian predominance and has been increasing in Northern hemisphere, especially in the United States (US) and Western Europe. It occurs more commonly in males in the fourth and fifth decades of life. Among all cancers, HCC is one of the fastest growing causes of death in the US and poses a significant ec...

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Hepatocellular Carcinoma: Epidemiology and Etiology

Davide Degli Esposti1,2, Morando Soffritti3,*, Antoinette Lemoine1,2, Eva Tibaldi3 and Marco Manservigi3 1AP-HP, Hôpital Paul Brousse, Service de Biochimie et Biologie Moléculaire, Inserm; Université Paris-Sud 11; PRES Universud-Paris; Paul Vaillant Couturier 2Laboratoire de Biochimie et Biologie Cellulaire, Faculté de Pharmacie, Université Paris-Sud 11, Jean Baptiste Clément 3Cesare Maltoni Ca...

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[Etiology and epidemiology of hepatocellular carcinoma].

Hepatocellular carcinoma (HCC) is a highly malignant tumour with a poor prognosis. Its incidence is rising. The estimate incidence worldwide is 1 million cases. Most frequently it develops in livers already affected by cirrhotic transformation. How cirrhosis predisposes for the development of HCC is not clear. It is probably associated with the increased DNA synthesis in regeneration nodules. I...

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Hepatocellular Carcinoma: Carcinogenesis, Establishment, Progression, and Therapies

Hepatocellular carcinoma (HCC) has had a continuous increase worldwide in incidence over the last two decades. The development of HCC has a complicated process and correlates to numerous risk factors including hepatitis virus infection, alcoholism, food toxins, diabetes, obesity, smoking, congenital liver diseases, and errors of metabolism. Molecular links are also identified, which characteriz...

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ژورنال

عنوان ژورنال: Journal of Carcinogenesis

سال: 2017

ISSN: 1477-3163

DOI: 10.4103/jcar.jcar_9_16